The Indiana University School of Medicine Department of Otolaryngology--Head and Neck Surgery, established in 1909, has a proud tradition of achievement in the areas of medical research, education and patient care. The faculty of this department treat diseases of the ear, nose and throat; research innovative new treatments; and educate the next generation of otolaryngology--head and neck surgeons.
Our researchers contribute regularly to the creation of new knowledge, understanding and treatments surrounding diseases of the ear, nose and throat. Faculty members in this department study various challenges in this area of medicine, such as understanding how hearing loss affects a child's developing brain, or how cachexia or unintentional weight loss affects cancer patients.
We currently have a Research Tecnhician I role available in the laboratory of Dr. RIck Nelson. For more information, visit here .
This laboratory team currently focuses on why serine proteases are critical for the survival of hair cells in the inner ear and what cellular pathways mediate hair cell degeneration and deafness. Currently, the goal of this research is to understand how type II transmembrane serine protease 3 (TMPRSS3) functions, to identify and define the mechanisms that lead to hair cell degeneration and to develop therapeutic strategies for deafness and balance disorders.
The Research Technician I provides general laboratory support and technical assistance at a senior level in the study of pathophysiology of the inner ear using a novel human stem cell-derived 3D inner ear organoid model in conjunction with genetic mouse models. In this key role, the incumbent will independently perform experiments and assays under instructions of the principal investigator. Experimental approaches being used in the lab include CRISPR/Cas9, single cell RNAseq, cell culture with live cell imaging, immunohistochemistry with confocal microscopy, Ca2+ imaging, coimmunoprecipitation and proteomics. The incumbent will collect, analyze and interpret data and use knowledge of laboratory procedures and protocols to make sound decisions and problem solve. The incumbent will also maintain laboratory organization/safety /equipment. The incumbent will primarily work on projects designed by the principal investigator and research team. This is an exciting opportunity to gain invaluable research experience under the direction of experts in the field.
Bachelor of Arts (BS) degree in biomedical sciences.
Ability to work independently and communicate with lab staff and investigators. Ability to maintain complete and organized reports/records. Knowledge of computer software and general lab equipment.
Working Conditions / Demands
Bench research laboratory. Must be able put in a full work day working at the laboratory bench, going from room to room for different tasks, where equipment and supplies are housed. The ability to do light lifting and moving to stock and re-stock supplies.
Must be able to perform the essential functions of the role with our without reasonable accommodation.
Must be able to work occasional nights and weekends.
Salary Plan: RS
Salary Grade: 07
Job Function: Research
Due to the COVID-19 pandemic, there may be differences in the working conditions as advertised in our standard job postings (e.g., the ability to travel from one campus to another, etc.). If you are invited for an interview, please discuss your questions or concerns regarding the working conditions at that time.
This posting is scheduled to close at 11:59 pm EST on the advertised Close Date. This posting may be closed at any time at the discretion of the University, but will remain open for a minimum of 5 business days. To guarantee full consideration, please submit your application within 5 business days of the Posted Date.
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Founded in 1820, Indiana University is the state’s public university system, comprised of two core campuses—IU-Bloomington and IUPUI—and six regional campuses located throughout the state. Combined, the total student population is more than 114,000 undergraduate, graduate and professional school students. IU is one of the largest employers in the state, with over 20,000 faculty and staff. Indiana University is an equal employment and affirmative action employer and a provider of ADA services. Diversity and inclusion remains a core commitment to IU’s mission to cultivate an educational environment that supports equal access, participation and representation on all of its campuses and that provides educational and career opportunities for all.